Membrane Protein In Urine Can Now Detect Brain Tumour

Early Detection Provides Better Outcomes

Researchers keep on finding new ways to detect any disease in the early stage so that it can be treated effectively. A team of researchers in Japan have now found a new way to detect brain tumour. They have developed a new device that can identify a key membrane protein in the urine that indicates if the patient has a brain tumour.

Associate Professor Takao Yasui and Professor Yoshinobu Baba led the group that developed the device. They all are from Japan-based Nagoya University and working on this in collaboration with the University of Tokyo. Together, they have developed a new analysis platform for brain tumour extracellular vesicles (EVs) using nanowires at the bottom of a well plate.

The Device will help Doctors Identify Tumour in Patients Even Before they Develop Symptoms.

The presence of tumour-related extracellular vesicles (EVs) in the urine of people can be one of the early signs that they have a brain tumour. A variety of functions, including cell-to-cell communication, are performed by EVs – which are nanoparticles.

These proteins are known as CD31 and CD63.

“Currently, more than two instruments and an assay are required for extracellular vesicles isolation and detection methods required to isolate and then detect EVs,” Yasui said.

Moreover, the researchers are of the view that the key membrane protein present in the urine could be also useful in detecting brain cancer. If this happens, it will eliminate the need for invasive tests. Also, the chances of tumours being detected early enough for surgery will be significantly higher.

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