According to a recent study conducted in the UK it has been found that Oxford AstraZeneca vaccines that are manufactured by the Serum Institute of India and is administered under the name Covishield, offer protection that may last a whole lifetime.
The vaccine just not generates antibodies against the SARS-COV-2 virus but also created “training camps” in the body in order to enable search-and-destroy T-cells to even kill new variants, the study found.
As reported by The Sun, the authors of the study are scientists from Oxford, UK, and Switzerland. who published in the Nature journal that adenovirus vaccines like those developed Oxford AstraZeneca and Johnson & Johnson can train the body to continue to make vital T-cells even from a long time after antibodies from the vaccine shot wane and it could possibly keep making them for life they say.
Researcher Prof Burkhard Ludewig, of Cantonal Hospital in Switzerland said, “The T-cells that come from these cellular training camps appear to have a very high level of ‘fitness’.”
He adds, “Adenoviruses have co-evolved with humans over a very long time, and learned a lot about the human immune system in the process.”
According to the study’s findings, adenoviruses have the ability to breach long-lived tissue cells. These cells, called fibroblastic reticular cells, can act as T-cell “training grounds”.
As per Prof Paul Klenerman, of Oxford’s Nuffield Department of Medicine, said: “Millions of people have received adenovirus vaccines around the world. The ultimate goal with these vaccines is the induction of long-term immune system protection using both antibodies and T-cells. This research helps us to understand more on the process of vaccination, and why the effects on killer T-cells are so prolonged.”
In comparison to Pfizer and Moderna, which are both mRNA vaccines Oxford AstraZeneca vaccine are more effective at generating the T-cells showed the results of the recent findings which adds weight to this new study.
