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WHO Study Reveals Nearly 1 In 10 Infants Are Born Prematurely With Significant Health & Survival Hazards

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Serbia, Moldova, and Kazakhstan were the least affected by preterm birth.
Serbia, Moldova, and Kazakhstan were the least affected by preterm birth.
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A detailed study that has been conducted by experts from the World Health Organization (WHO) and the London School of Hygiene and Tropical Medicine has shown that in 2020 around 13.4 million infants were born prematurely, which means before 37 full weeks of pregnancy. 13.4 million premature infants account for 1 baby in 10 of all live births. The findings of the study have been released in the Lancet today.

Premature birth is the main cause of infants’ death in early years

As per the report, early birth or premature birth is the main cause of infants’ death in early years. Experts say that there is a pressing need for preventive efforts to strengthen preterm baby care and maternal health and nutrition. Preterm birth also leads to an increased risk of development delays, chronic diseases in adulthood such as diabetes and heart issues, major ailments, and other disabilities.

The study has revealed that India accounted for 3.02 million preterm births in 2020, which is the highest number of preterm births in the world. India contributes to more than 20 per cent of all preterm births worldwide. Other trends linked to maternal health show that no region in the world has recorded any major reductions in the rate of preterm births in the last 10 years. The annual worldwide rate of reduction in preterm births from 2010 to 2020 was just 0.14 per cent. Health experts say that it is essential to ensure access to valued health care before and during every pregnancy.

The study has offered national, regional, and global estimates of preterm birth in 2020. The findings reveal major inequalities between regions and countries. Sub-Saharan Africa accounted for about 65 per cent of premature births in 2020. Southern Asia contributed to more than 13 per cent of pre-term births. Bangladesh, Pakistan, and Malawi were found to be the most affected countries with premature birth rates of 16.2 per cent, 14.3 per cent, and 14.5 per cent respectively.

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Serbia, Moldova, and Kazakhstan were the least affected by preterm birth. Premature birth equally affects low and high-income nations. In high-income countries such as Greece and the US, rates of preterm birth were found to be 11. 6 percent and 10 percent correspondingly.

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The Nipah virus is considered one of the deadliest zoonotic infections globally, not because it spreads rapidly like influenza or COVID-19, but because of its extremely high fatality rate, rapid progression, and severe brain involvement. Medical experts warn that once symptoms escalate, the disease can turn fatal within days. According to available data, the case fatality rate of Nipah virus ranges between 50 and 75 per cent, placing it among the most lethal viral infections known to humans. In this explainer, Dr Dip Narayan Mukherjee, Consultant – Microbiology and Infectious Diseases, CK Birla Hospitals, CMRI, sheds light on why the virus is so dangerous and difficult to control. Why Is the Nipah Virus So Deadly? According to Dr Mukherjee, Nipah’s lethality lies in a combination of delayed symptom recognition, aggressive disease progression, and early involvement of the brain. “Nipah virus often begins with very non-specific symptoms, which makes early detection difficult. By the time it is clinically suspected, the virus may have already affected the brain,” he explains. Early Symptoms Often Go Unnoticed One of the biggest challenges in controlling Nipah virus is that its initial symptoms closely resemble common viral illnesses, leading to delays in diagnosis and isolation. Early symptoms include: Fever Headache Cough Muscle pain General weakness “These symptoms are easily mistaken for flu, viral fever, or respiratory infections,” says Dr Mukherjee. “This delay gives the virus time to progress silently.” Severe Brain Infection Drives High Mortality The most dangerous aspect of Nipah virus infection is its neurological involvement. The virus frequently causes encephalitis, or inflammation of the brain, which significantly increases the risk of death. Neurological symptoms may include: Seizures Confusion and altered consciousness Extreme drowsiness Coma “Once the central nervous system is involved, the disease becomes very difficult to manage,” Dr Mukherjee notes. “At this stage, treatment is largely supportive because there is no specific antiviral therapy available.” This lack of targeted treatment options makes early detection critical. Human-to-Human Transmission Raises Risk While Nipah virus is primarily transmitted from fruit bats, it can also spread from person to person, particularly in healthcare settings. Dr Mukherjee points out that: Caregivers and healthcare workers are at higher risk Exposure to high viral loads can worsen outcomes Inadequate infection control increases transmission risk “Strict adherence to infection control practices is essential. Even a small lapse can result in secondary infections,” he says. Zoonotic Nature Makes Exposure Hard to Predict Nipah virus is transmitted from fruit bats, either directly or through intermediate hosts such as pigs. This zoonotic pattern makes outbreaks unpredictable, especially in regions where humans, animals, and wildlife interact closely. Adding to the challenge: There is no approved vaccine Treatment options remain limited Isolation protocols must be strictly enforced What Can Reduce Nipah Fatalities? According to experts, early action remains the most effective defence against Nipah virus. Key measures include: Early isolation of suspected cases Strict use of personal protective equipment (PPE) Rapid escalation and referral to specialised centres Strong hospital infection control protocols “The earlier the virus is identified and contained, the better the chances of preventing severe disease and fatalities,” Dr Mukherjee emphasises. The Bottom Line Nipah virus continues to be a serious public health threat because of its high fatality rate, neurological complications, and lack of targeted treatment. Its ability to masquerade as a mild illness in the early stages makes vigilance crucial. Health experts stress that awareness, early suspicion, and strict infection control are currently the most powerful tools to reduce deaths linked to this deadly virus. As Dr Mukherjee concludes, “With Nipah, time is the most critical factor. Early recognition can save lives.”
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