A new study has found that a plant-based compound known as Cytisine might be more effective as compared to nicotine substitution therapy in helping people quit smoking. The findings of the study have been released in a journal called Addiction. Experts say that the plant-based element also reduces withdrawal symptoms of smoking. This compound is less expensive and has been used in Eastern Europe since the 1960s for smoking cessation. As per the findings, this stop-smoking aid has a benevolent safety profile and there is no evidence of adverse safety issues. The lead author of the study, Omar De Santi says that although cytisine is yet not certified or sold in several countries of Europe, expanding its availability across the world, especially in low- and middle-income nations might make a huge difference to global health.
This plant-based compound was synthesized in Bulgaria in 1964 as Tabex for the first time and later it became available to other nations in Eastern Europe and Asia. A Polish pharmaceutical firm called Aflofarm started marketing it in 2017 as Desmoxan, which is a prescription-only medicine, and Canada also authorized it as an over-the-counter natural health medication known as Cravv. The authors of the study say that as it is a less expensive drug, it can be included in a strategy to expand the availability of drug therapy for smokers, particularly in low- and middle-income nations.
This study included the findings of eight randomized controlled trials and compared cytisine with placebo on around 6000 people. A comprehensive analysis showed that cytisine elevates the odds of effective smoking cessation by over twofold as compared to placebo. Experts say that this plant-based compound might be quite useful in decreasing the rate of smoking in low- and middle-income nations where cost-effective smoking termination drugs are urgently required. Smoking is characterized as the major cause of preventive fatalities across the globe.
Leave a comment