New Delhi, 04 June 2025: Silicon Valley biohacker Bryan Johnson—famous for spending millions to reverse aging—has made yet another bold claim. After undergoing an intense 90-day oxygen therapy regimen, Johnson says he now has the “biology of a 10-year-old”—a statement that has stirred both intrigue and skepticism across the medical and tech worlds.
Johnson, 46, is no stranger to controversy. The tech millionaire has been documenting his extreme anti-aging project, “Project Blueprint,” for years, drawing global attention for his unorthodox methods—from plasma transfusions to strict dietary and sleep regimens. But this latest announcement takes things to a new level.
What Is Hyperbaric Oxygen Therapy (HBOT)?
At the heart of Johnson’s latest experiment is hyperbaric oxygen therapy (HBOT), a treatment traditionally used for wound healing, decompression sickness, and carbon monoxide poisoning.
The process involves breathing pure oxygen in a pressurized chamber, which increases oxygen availability in the body. This is believed to promote tissue regeneration, improve brain function, and stimulate stem cell production—all highly sought-after outcomes in anti-aging science.
According to Johnson, his daily HBOT sessions for 90 days straight have resulted in profound biological changes.
“I Have the Biology of a 10-Year-Old,” Says Johnson
In a recent post to his 450,000+ followers, Johnson wrote: “After 90 days of oxygen therapy, my body is functioning like that of a 10-year-old. Skin, muscles, metabolism, even inflammation markers—rejuvenated.” He claims that his biological markers, including epigenetic age, skin elasticity, metabolic rate, and inflammation levels, now match or outperform those of a pre-teen. These statements, while unverified by third-party medical reviews, are in line with Johnson’s ongoing goal: to achieve biological immortality or “don’t die” science—as he often puts it.
The Science: Can Oxygen Therapy Really Reverse Aging?
HBOT has shown promise in limited clinical studies related to age reversal. In 2020, an Israeli study published in Aging journal found that hyperbaric oxygen therapy lengthened telomeres—protective caps on chromosomes associated with biological aging—and reduced senescent (aged) cells in healthy aging adults.
But most scientists caution that these findings are preliminary. Dr. Avinash Desai, a cellular aging expert in Delhi, said: “There is growing interest in oxygen therapy for anti-aging, but claims of a 10-year-old’s biology are scientifically premature. We need larger, controlled trials.” Still, Johnson’s multimillion-dollar experiments are helping spark mainstream interest in biohacking and regenerative medicine, pushing boundaries of what’s possible—and what might be hype.
Johnson’s Project Blueprint: A Look at His Full Anti-Aging Routine
Oxygen therapy is just one component of Bryan Johnson is elaborate anti-aging lifestyle. Project Blueprint is a highly regimented system, which includes:
- Vegan diet with strict calorie tracking (under 2,000 per day)
- Over 100 daily supplements and medications
- Early bedtime and wake-up routine (4:30 am)
- Exercise, resistance training, and HIIT
- Daily diagnostics, including blood, MRI, and ultrasound tests
- Occasional plasma transfusions, including receiving his son’s plasma (a practice later discontinued)
Johnson claims this system has slowed his pace of aging by 31 years, meaning his organs now reflect those of someone in their late teens or early 20s.
The Future of Longevity: Hope or Hype?
Johnson’s latest HBOT experiment is the newest chapter in the emerging science of longevity. From gene editing and stem cells to artificial intelligence and blood biomarkers, the field is exploding with innovation.
But for now, mainstream medicine still advises balanced living, good sleep, plant-based diet, exercise, and regular check-ups as the most effective and proven ways to live longer, healthier lives.
Bryan Johnson is claim of achieving a child-like biological age through oxygen therapy may sound extraordinary—even unbelievable—but it reflects a growing ambition in biohacking: not just to slow aging but to stop it altogether.
Whether science will eventually validate his methods or debunk them as exaggerated remains to be seen. But Johnson is undoubtedly pushing humanity to ask one of its oldest questions in a new way: Can we really live forever—and should we?
